{"created":"2024-06-25T03:02:02.409397+00:00","id":2000123,"links":{},"metadata":{"_buckets":{"deposit":"d02de86a-f6c7-426f-8bdd-3bb5f9bb059b"},"_deposit":{"created_by":11,"id":"2000123","owner":"11","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"2000123"},"status":"published"},"_oai":{"id":"oai:kinjo.repo.nii.ac.jp:02000123","sets":["113","113:18","113:18:1719192528703"]},"author_link":[],"control_number":"2000123","item_10002_biblio_info_7":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2024-03-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"6","bibliographicPageStart":"1","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"金城学院大学論集. 自然科学編","bibliographic_titleLang":"ja"},{"bibliographic_title":"Treatises and Studies by the Faculty of Kinjo Gakuin University. Studies in Natural Sciences","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"薬学部における化学系実習と薬理系実習の連携を図るため，学生が化学合成した薬物が薬理活性を有しているか調べた。本評価では，学生が合成をした気管支喘息治療薬であるtheophyllineを用いた。Histamineで収縮させたモルモット気管平滑筋は，学生が合成したtheophyllineによって弛緩した。このことから，化学系実習で合成したtheophyllineは，薬理活性を有していること示された。以上のことは，化学系実習と薬理系実習が連携する薬学部独特の新たな実習形態を構築することができることを示唆する。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_10002_identifier_registration":{"attribute_name":"identifier_registration","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.69275/0002000123","subitem_identifier_reg_type":"JaLC"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"金城学院大学","subitem_publisher_language":"ja"}]},"item_10002_source_id_9":{"attribute_name":"item_10002_source_id_9","attribute_value_mlt":[{"subitem_source_identifier":"18800378","subitem_source_identifier_type":"PISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"安東, 嗣修","creatorNameLang":"ja"},{"creatorName":"ANDOH, Tsugunobu","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"福石,信之","creatorNameLang":"ja"},{"creatorName":"FUKUISHI, Nobuyuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"坂梨, まゆ子","creatorNameLang":"ja"},{"creatorName":"SAKANASHI, Mayuko","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"青柳, 裕","creatorNameLang":"ja"},{"creatorName":"AOYAGI, Yutaka","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"渡邉, 真一","creatorNameLang":"ja"},{"creatorName":"WATANABE, Shin-Ichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"永津, 明人","creatorNameLang":"ja"},{"creatorName":"NAGATSU, Akito","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-07-08"}],"filename":"01_Tsugunobu ANDOH, Nobuyuki FUKUISHI, Mayuko SAKANASHI, Yutaka AOYAGI, Shin-Ichi WATANABE, Akito NAGATSU.pdf","filesize":[{"value":"2 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://kinjo.repo.nii.ac.jp/record/2000123/files/01_Tsugunobu ANDOH, Nobuyuki FUKUISHI, Mayuko SAKANASHI, Yutaka AOYAGI, Shin-Ichi WATANABE, Akito NAGATSU.pdf"},"version_id":"441ac2c2-f46d-4d59-9886-eaa60656ffd2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"item_resource_type","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"化学実習と薬理学実習の連携を目指した， 学生が合成した化合物の薬理活性の評価 ： 気管支喘息治療薬テオフィリンの合成と気管平滑筋弛緩作用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"化学実習と薬理学実習の連携を目指した， 学生が合成した化合物の薬理活性の評価 ： 気管支喘息治療薬テオフィリンの合成と気管平滑筋弛緩作用","subitem_title_language":"ja"},{"subitem_title":"Evaluation of pharmacological activity of chemical compound synthesized by students,  aiming at collaboration between chemistry practice and pharmacological practice ： Synthesis of bronchial asthma drug theophylline and its relaxing effect on tracheal smooth muscle","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"11","path":["113","18","1719192528703"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-07-08"},"publish_date":"2024-07-08","publish_status":"0","recid":"2000123","relation_version_is_last":true,"title":["化学実習と薬理学実習の連携を目指した， 学生が合成した化合物の薬理活性の評価 ： 気管支喘息治療薬テオフィリンの合成と気管平滑筋弛緩作用"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2025-07-30T01:56:05.169127+00:00"}